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Volume ratio and distribution rate in patients with orthostatic vertigo/dizziness using MR imaging: a comparison with
Hiroshi Inui1, Tsuyoshi Sakamoto2, Keita Ueda3
1Inui ENT Clinic, Sakurai City, Nara, Japan.
Background:
Orthostatic dizziness/vertigo (ODV) is characterized by lightheadedness owing to postural changes.
Aims/Objectives:
To measure the endolymphatic space (ELS)/total fluid space (TFS) volume ratio and the distribution rate of endolymphatic fluid (ELF) of patients with ODV and compare them with those of control subjects (CS).
Materials And Methods:
This study included 22 patients (44 ears) with ODV and 52 controls (104 ears, CS). The ELS/TFS volume ratio (%) and distribution rate (%) of the inner ear components were measured using 3-dimensional magnetic resonance imaging.
Results:
In the ODV group, the mean ELS/TFS volume ratios of the cochlea, vestibule, and semi-circular canals (SCCs) were 12.1%, 18.6%, and 18.1%, respectively; the mean ELS distribution rates for the cochlea, vestibule, and SCCs were 27.3%, 26.2%, and 46.6%, respectively. The ELS distribution rate of the vestibule was significantly lower (p < .01) and the ELS distribution rate of the SCCs was significantly higher in the ODV than in the CS group (p < .01).
Conclusions And Significance:
The ELS distribution rate in the vestibule + SCCs among patients with ODV did not differ from that in the CS; ELF in the vestibule moved to the SCCs, and a large amount of ELF was distributed only in the SCCs.
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