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Related Experiment Video

Updated: Jul 20, 2025

Quantitating Iron Transport Across the Mouse Placenta In Vivo Using Nonradioactive Iron Isotopes

Quantitating Iron Transport Across the Mouse Placenta In Vivo Using Nonradioactive Iron Isotopes

Published on: May 10, 2022

Iron deficiency, pregnancy, and neonatal development.

Ricardo Ataide^1,2, Katherine Fielding¹, Sant-Rayn Pasricha^1,3,4,5

¹Population Health and Immunity Division, The Walter and Eliza Hall Institute, Melbourne, Australia.

International Journal of Gynaecology and Obstetrics: the Official Organ of the International Federation of Gynaecology and Obstetrics

|August 4, 2023

Summary

Iron deficiency anemia impacts pregnant women globally. This review explores how iron deficiency affects maternal and infant health, highlighting the need for more human studies to improve outcomes.

Keywords:

anemia growth infection iron iron deficiency neonate placenta pregnancy

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Last Updated: Jul 20, 2025

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Measurement of Tissue Non-Heme Iron Content using a Bathophenanthroline-Based Colorimetric Assay

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Published on: January 31, 2022

Area of Science:

Obstetrics and Gynecology
Maternal-Fetal Medicine
Nutritional Science

Background:

Anemia affects 36% of pregnant women globally, with 40% of cases stemming from iron deficiency (ID).
Iron is crucial for erythropoiesis, immune function, and placental/fetal development during pregnancy.
Menstrual bleeding can contribute to ID before pregnancy, but this review focuses on the pregnancy period.

Conclusions:

More human studies are essential to fully understand iron regulation and the effects of ID during pregnancy.
Advances in research are needed to develop effective strategies for reducing ID incidence in pregnant women.
Improving maternal and infant health outcomes hinges on better management of iron deficiency during pregnancy.