Related Experiment Video
Updated: Jul 20, 2025

A Minimally Invasive Model to Analyze Endochondral Fracture Healing in Mice Under Standardized Biomechanical Conditions
Published on: March 22, 2018
Comparative Bending Strength of Metacarpal Neck Fractures Fixed with Two Types of Intramedullary Screws
Christopher M Jones1, Rena Mathew2, Nicholas Anastasi2
1Rothman Orthopaedic Institute at Thomas Jefferson University, Philadelphia, Pennsylvania, USA.
Objectives:
Intramedullary (IM) screw fixation of metacarpal fractures is a technique, which has gained in popularity owing to its simplicity, speedy rehabilitation, and good functional outcomes. A new, larger diameter, non-compression screw designed specifically for IM metacarpal fixation was recently introduced which could provide better fracture stability and reduce the risk of hardware failure. Our goal was to evaluate the strength of this screw compared to a first-generation screw.
Methods:
This mechanical study was designed to compare a 4.5 mm metacarpal headless screw (MCHS) to data from our prior research evaluating a 3.0 mm headless screw (HS). Accordingly, we used identical bone models, testing constructs, equipment, and protocols. A metacarpal neck osteotomy was created in 10 Sawbones models. A 4.5 mm x 50 mm MCHS was inserted retrograde to stabilize the fracture. Flexion bending strength was measured through a cable tension construct on a materials testing machine. Failure mechanism and strength was recorded and compared to data with a 3.0 mm screw construct.
Results:
Eight models failed by bending of the intramedullary screw. Two models failed by rotation of the metacarpal head. Failure occurred at an average of 539 N (Range 315 - 735 N). The MCHS demonstrated a significantly greater load to failure compared to the previously studied 3.0 mm HS at 215 N (P<0.05).
Conclusion:
A larger, 4.5 mm metacarpal-specific headless screw is more than twice as strong as a 3.0 mm diameter screw in a metacarpal neck fracture model.
More Related Videos
04:19Minimally Invasive Treatment for Thoracolumbar Burst Fracture Using Sagittal Alignment Screws and A Trauma Reduction Device
Published on: November 8, 2024
07:41An Intramedullary Locking Nail for Standardized Fixation of Femur Osteotomies to Analyze Normal and Defective Bone Healing in Mice
Published on: November 13, 2016