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Updated: Jul 20, 2025

Quantitative Autonomic Testing
Published on: July 19, 2011
Sudden onset anhidrosis in an otherwise healthy male
Clara Michelle Tan Hwei Sian Tan1, Rayson Lee2, Janet Pei Ling Dua3
1National University of Singapore Yong Loo Lin School of Medicine Singapore Singapore.
Abstract:
Acquired idiopathic generalised anhidrosis (AIGA) is a rare disorder that is characterised by sudden onset generalised absence of sweating without any dermatological, neurological or sweat gland abnormalities. AIGA predominately affects young males, mostly involving patients of Asian descent. There have been approximately 100 reported cases worldwide, most of which were reported in Japan. In Singapore, it is rarely seen with one case series on 15 cases of AIGA reported in a 2014 study. Here, we present a case of AIGA who responded well to conservative management with sweating activity.
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