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Multiple Bowen's disease on the finger associated with human papillomavirus type 34

Satoru Yonekura1, Gyohei Egawa1, Takaya Komori1

  • 1Department of Dermatology Kyoto University Graduate School of Medicine Kyoto Japan.

Skin Health and Disease
|August 4, 2023
PubMed

Insights

Human papillomavirus (HPV) infection may increase the risk of Bowen's disease. A case study identified HPV-34 in a patient with finger Bowen's disease, highlighting the potential for multiple lesions.

Area of Science:

  • Dermatology
  • Virology
  • Oncology

Background:

  • Bowen's disease, a form of squamous cell carcinoma in situ, is associated with human papillomavirus (HPV) infection.
  • The role of HPV in the development of cutaneous Bowen's disease, particularly on digits, requires further investigation.

Observation:

  • A case of Bowen's disease on the finger of a 40-year-old male patient was documented.
  • The observed lesion exhibited a discontinuous, skip pattern, which is atypical for this condition.

Findings:

  • Human papillomavirus type 34 (HPV-34) was detected within the affected tissue.
  • The presence of HPV-34 in a skip lesion of finger Bowen's disease suggests a potential link between specific HPV types and lesion morphology.

Implications:

  • This case underscores the importance of considering multifocal or discontinuous lesions in the differential diagnosis of finger Bowen's disease.
  • Further research into HPV types and their association with varied clinical presentations of Bowen's disease is warranted.
  • Early detection and management of HPV-related skin conditions are crucial for patient outcomes.

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