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Improving clinical trial recruitment with warm transfers
Kyle Peer1, Jonathan Cotliar1, Andrew Goulian1,2
1Science 37, Culver City, CA, USA.
Digital Health
|August 4, 2023
Summary
Warm transfers significantly increased clinical trial enrollment for high-risk COVID-19 patients. Real-time connection to research staff improved participant recruitment compared to scheduled callbacks.
Area of Science:
- Clinical research methodology
- Infectious disease epidemiology
Background:
- Decentralized clinical trials present unique recruitment challenges.
- Effective patient engagement strategies are crucial for trial success, especially in high-risk populations.
Purpose of the Study:
- To compare the enrollment rates between real-time "warm" transfers and arranged callbacks for potential participants in a COVID-19 clinical trial.
- To identify optimal recruitment strategies for large, decentralized clinical studies.
Main Methods:
- Retrospective analysis of 2341 respondents in a COVID-19 clinical trial.
- Comparison of enrollment success rates based on two distinct recruitment pathways: immediate transfer versus scheduled callback.
Main Results:
- Respondents who experienced a warm transfer demonstrated a significantly higher likelihood of enrolling in the clinical trial.
- The warm transfer method proved more effective in converting interested individuals into trial participants.
Conclusions:
- Real-time, direct connection with clinical research coordinators (warm transfers) is a superior method for enhancing participant enrollment in decentralized clinical trials.
- Implementing warm transfer protocols can optimize recruitment efficiency and potentially accelerate research for critical health conditions like COVID-19.
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