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Updated: Jul 20, 2025

Assessment of Bone Fracture Healing Using Micro-Computed Tomography
Published on: December 9, 2022
Validation of the Radiographic Union Score for HUmeral fractures (RUSHU): A retrospective study in an independent
William Fordyce1, Grace Kennedy1, James R Allen1,2
1Trauma and Orthopaedics, Derriford Hospital, University Hospitals Plymouth NHS Trust, Plymouth, UK.
Background:
Early diagnosis and fixation of fractures unlikely to unite can prevent months of morbidity. The Radiographic Union Score for Humeral fractures (RUSHU) is a summative scoring system developed to aid identification of patients at higher risk of developing humeral shaft non-union. Plain radiographs taken six weeks after injury are given a score between four and 12 based on signs of union. Our aim was to assess the validity of the RUSHU prognostic model in an external population.
Methods:
The radiographs of fifty-seven patients were scored independently according to RUSHU methodology by three reviewers (blinded to patient outcome). Interobserver intraclass correlation (ICC) was calculated.
Results:
Of the cohort, six (10.5%) progressed to non-union after six months. We observed an interobserver ICC co-efficient of 0.89 (95%CI0.84,0.93) in RUSHU score at six weeks. Median score was significantly higher in the union cohort (10v5 p < 0.001). Using the score of < 8 to predict non-union gave an area under the ROC curve of 0.87 (95%CI 0.83,0.90).
Conclusions:
In this retrospective single-centre study, we have demonstrated good inter-rater reliability. We would suggest that the RUSHU model be assessed in further external validation studies. RUSHU has the potential to reduce morbidity of delayed treatment of non-union.

