A new binuclear Ni(II) complex, an effective A³-coupling catalyst in solvent-free condition

Area of Science:

• Inorganic Chemistry
• Organic Synthesis
• Catalysis

Background:

• Binuclear metal complexes offer unique catalytic properties.
• Propargylamines are valuable synthetic intermediates.
• Solvent-free reactions are desirable for green chemistry.

Purpose of the Study:

• To synthesize and characterize a novel binuclear nickel(II) complex.
• To investigate the catalytic activity of the complex in organic synthesis.
• To explore the reusability of the catalytic system.

Main Methods:

• Synthesis of [Ni2(en)4(ox)](ClO4)2 (1) from nickel(II) chloride, ethylenediamine, ammonium oxalate, and sodium perchlorate.
• X-ray crystallography and infra-red spectroscopy for structural determination.
• One-pot reaction of aldehydes, amines, and acetylenes under solvent-free conditions.

Main Results:

• Successful isolation and structural elucidation of the binuclear nickel(II) complex.
• Efficient one-pot synthesis of propargylamines with good yields.
• Demonstration of catalyst reusability over five reaction cycles.

Conclusions:

• The newly synthesized binuclear nickel(II) complex is an effective catalyst for propargylamine synthesis.
• The catalytic system is efficient, operates under solvent-free conditions, and is reusable.
• This work presents a sustainable approach to propargylamine synthesis.