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Second primary carcinoma arising on a flap: a new primary or a relapse?
Gerardo Petruzzi1, Teodosio De Bonis2, Valentina Manciocco3
1Gerardo Petruzzi: Department of Otolaryngology, Head and Neck Surgery, IRCCS Regina Elena National Cancer Institute, Rome, Italy.. petruzzigerardo@gmail.com.
Acta Bio-Medica : Atenei Parmensis
|August 4, 2023
Summary
A rare secondary primary cancer can develop on head and neck reconstruction flaps. Persistent oral stimuli may cause these secondary primary tumors, necessitating consideration in patient follow-up.
Area of Science:
- Oncology
- Head and Neck Surgery
- Reconstructive Surgery
Background:
- Free and pedicle flaps are standard for head and neck cancer reconstruction.
- Long-term complications of these flaps, particularly secondary tumors, are not well understood.
- Secondary primary tumors on flaps are rare but concerning events.

