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Outpatient CD28-costimulated CAR T-cells for B-cell malignancies with CNS involvement

Khaled Sanber1, Andrew Ly2, Angela Ondo1

  • 1Division of Hematological Malignancies and Bone Marrow Transplantation, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, Maryland, USA.

American Journal of Hematology
|August 4, 2023
PubMed
Abstract

No abstract available in PubMed .

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Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
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