Ambient Temperature and Cardiac Biomarkers: A Meta-Analysis.

Area of Science:

• Environmental Health
• Cardiovascular Medicine
• Biomarker Research

Background:

• Ambient temperature fluctuations are increasingly recognized as environmental stressors impacting human health.
• Cardiac biomarkers play a crucial role in diagnosing and assessing cardiovascular disease (CVD) risk.
• Understanding the relationship between ambient temperature and cardiac biomarkers is vital for public health management.

Approach:

• A systematic meta-analysis was conducted following PRISMA guidelines, synthesizing data from peer-reviewed studies.
• Studies published between January 2000 and February 2022 were retrieved from major scientific databases (MEDLINE, ScienceDirect, Google Scholar).
• Random-effects meta-analysis quantified the pooled effect sizes of ambient temperature changes on various cardiac biomarkers and blood pressure.

Key Points:

• A 1°C decrease in ambient temperature correlated with a 0.31% increase in cardiac biomarkers.
• A 1°C increase in ambient temperature correlated with a 2.03% increase in cardiac biomarkers.
• The impact on cardiac biomarkers was more pronounced in the cardiovascular patient population.

Conclusions:

• Ambient temperature, both cold and heat, directly correlates with alterations in key cardiac biomarkers.
• These findings underscore the significant role of temperature in cardiovascular health and mortality.
• The study provides valuable insights for managing temperature-associated cardiovascular risks.