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Updated: Jul 20, 2025

Perturbations of Circulating miRNAs in Irritable Bowel Syndrome Detected Using a Multiplexed High-throughput Gene Expression Platform
Published on: November 30, 2016
What is new with irritable bowel syndrome
Hebat Y Kamal1, Kayla Morneault-Gill, Christina B Chadwick
1Division of Pediatric Gastroenterology, Hepatology, and Nutrition, University of Florida College of Medicine, Gainesville, Florida, USA.
Pediatric irritable bowel syndrome (IBS) is a common cause of childhood abdominal pain. This review summarizes current diagnostic criteria and multifaceted treatment strategies to improve quality of life for affected children.
Area of Science:
- Pediatric Gastroenterology
- Functional Gastrointestinal Disorders
Background:
- Irritable bowel syndrome (IBS) is a prevalent functional gastrointestinal disorder in children, frequently presenting as a primary cause of abdominal pain.
- The condition significantly impacts a child's quality of life due to its debilitating nature and the challenges in achieving consistent symptom relief.
- Understanding the diverse triggers and pathophysiology of pediatric IBS is crucial for effective management.
Conclusions:
- Pediatric IBS necessitates individualized management strategies.
- Treatment plans may incorporate dietary modifications, probiotics, pharmacotherapy, and psychotherapy.
- Further research is essential to establish definitive treatment protocols and improve patient outcomes.
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