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Oxford brain health clinic: protocol and research database
Melissa Clare O'Donoghue1,2, Jasmine Blane1,2, Grace Gillis1,2
1Department of Psychiatry, University of Oxford, Oxford, UK.
BMJ Open
|August 4, 2023
Summary
The Oxford Brain Health Clinic (BHC) integrates clinical care and research, offering standard MRI scans to memory clinic patients. This approach improves dementia research by including diverse patient populations and enhancing data quality for brain health initiatives.
Area of Science:
- Neuroscience
- Clinical Neurology
- Medical Imaging
Background:
- Advances in neuroscience have not improved dementia assessment quality.
- Dementia biomarker research often uses unrepresentative samples.
- Memory clinics serve a diverse patient population with memory problems.
Purpose of the Study:
- Introduce the Oxford Brain Health Clinic (BHC) protocol.
- Evaluate the feasibility of integrated clinical and research assessments in a memory clinic setting.
- Assess patient consent rates and tolerability for research participation.
Main Methods:
- Developed the BHC protocol, aligning MRI scans with UK Biobank standards.
- Collected data from the first 108 patients presenting to a memory clinic.
- Assessed patient consent and tolerability for clinical and research procedures.
Main Results:
- The BHC protocol facilitates high-quality clinical and research assessments for typical memory clinic patients.
- The integrated approach achieved high consent rates for research participation.
- Patients tolerated both clinical and research assessments effectively.
Conclusions:
- The BHC model successfully integrates research into standard clinical care for memory problems.
- This approach enhances dementia research by utilizing diverse patient data.
- The BHC protocol provides a scalable model for improving brain health research and patient care.
