Related Experiment Video
Updated: Jul 20, 2025
03:05
Author Spotlight: Advancing Early Detection and Treatment of Gastrointestinal Tumors
Published on: February 16, 2024
1.1K
Streptococcus Mitis Endocarditis Associated with Early Gastric Carcinoma.
Shigeaki Aoyagi1, Satoru Tobinaga1, Kumiko Wada1
1Department of Cardiovascular Surgery, St. Mary's Hospital.
The Kurume Medical Journal
|August 6, 2023
Summary
This case study highlights a rare Streptococcus mitis endocarditis linked to early gastric cancer. This finding suggests a potential association between this specific bacteria and gastrointestinal malignancies.
Area of Science:
- Cardiology
- Infectious Diseases
- Gastroenterology
Background:
- A 71-year-old male with a history of aortic regurgitation (AR) presented with elevated inflammatory markers.
- The patient had a history of atrophic gastritis, early gastric adenocarcinoma, and colon polyp diagnosed via endoscopy.
Observation:
- Severe AR and aortic valve vegetation were identified via echocardiography.
- Cerebral embolism and spondylodiscitis were noted on magnetic resonance imaging.
- Blood cultures confirmed Streptococcus mitis infection.
Findings:
- Surgical findings revealed destruction and vegetation on the aortic valve, necessitating aortic valve replacement.
- The patient had no recent oral procedures or dental issues, ruling out common sources of endocarditis.
Implications:
- This case underscores a potential, though less common, association between Streptococcus mitis endocarditis and gastrointestinal carcinoma.
- Clinicians should consider gastrointestinal malignancy in patients with Streptococcus mitis endocarditis, especially when other sources are absent.
Related Concept Videos
01:25Endocarditis I: Introduction
12
Introduction:Endocarditis is the infection of the endocardium, the inner lining of the heart and its valves. When the heart muscle is involved, the condition is termed myocarditis, while an infection of the outer lining is called pericarditis. Infective endocarditis (IE) primarily affects the endocardium, where pathogens adhere to the valves or lining, forming vegetation that can lead to severe complications. Infective endocarditis occurs when microorganisms, usually bacteria from other body...
12
01:22Mitral Stenosis I: Introduction
16
Mitral Valve Stenosis (MVS) is a heart condition where the mitral valve narrows, impeding blood circulation from the left atrium to the left ventricle. The etiology and pathophysiology of this condition are multifaceted, leading to a cascade of cardiovascular complications.Causes of Mitral Valve StenosisRheumatic Heart Disease: It is the main cause of mitral valve stenosis, particularly in developing nations. This condition arises from rheumatic fever, an inflammatory illness resulting from...
16
01:25Endocarditis II: Clinical Features of Infective Endocarditis
14
Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
14
01:17Gastritis-II: Pathophysiology
375
Gastritis is marked by disruption of the mucosal barrier that usually protects the stomach tissue from digestive juices and manifests in acute and chronic forms.
In acute gastritis, the gastric mucosa becomes swollen and red and undergoes superficial erosion. Superficial ulceration may lead to bleeding.
In chronic gastritis, persistent or repeated insults lead to chronic inflammatory changes and, eventually, thinning or atrophy of the gastric tissue.
Gastritis can stem from various causes, each...
In acute gastritis, the gastric mucosa becomes swollen and red and undergoes superficial erosion. Superficial ulceration may lead to bleeding.
In chronic gastritis, persistent or repeated insults lead to chronic inflammatory changes and, eventually, thinning or atrophy of the gastric tissue.
Gastritis can stem from various causes, each...
375
01:26Mitral Stenosis III: Medical Management
13
Mitral stenosis, a condition marked by the narrowing of the mitral valve, necessitates an integrated approach for effective management. This approach includes preventative measures, medical therapy, and surgical interventions to reduce symptoms and prevent complications.PreventionPrevention of mitral stenosis primarily focuses on reducing the incidence of bacterial infections, particularly streptococcal infections, which can lead to rheumatic fever and subsequent valvular damage. Timely...
13
01:23Gastritis III: Clinical Manifestations and Management
326
The clinical manifestations of gastritis can vary depending on the cause and type of gastritis, but some common symptoms may include the following.
Clinical manifestations of acute gastritis
The patient with acute gastritis may have a rapid onset of symptoms, such as epigastric pain or discomfort, dyspepsia, anorexia, hiccups, or nausea and vomiting, which can last from a few hours to a few days. Erosive or hemorrhagic gastritis may cause bleeding, which may manifest as blood in vomit or as...
Clinical manifestations of acute gastritis
The patient with acute gastritis may have a rapid onset of symptoms, such as epigastric pain or discomfort, dyspepsia, anorexia, hiccups, or nausea and vomiting, which can last from a few hours to a few days. Erosive or hemorrhagic gastritis may cause bleeding, which may manifest as blood in vomit or as...
326