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Variation in Organizational Clinical Practice Guidelines for Croup
Kelly R Bergmann1,2, Brian Lefchak1,2, Amanda Nickel3
1Departments of Pediatric Emergency Medicine.
Insights
Clinical practice guidelines (CPGs) for croup vary significantly among US children's hospitals. This study highlights inconsistencies in racemic epinephrine use and observation times, suggesting a need for standardization.
Area of Science:
- Pediatric Emergency Medicine
- Clinical Practice Guidelines
- Respiratory Illnesses
Background:
- Croup is a frequent pediatric emergency department (ED) diagnosis.
- Limited understanding exists regarding current clinical practice guidelines (CPGs) for croup management.
- Variability in CPGs can impact patient care and outcomes.
Purpose of the Study:
- To investigate the prevalence and characteristics of croup CPGs in US children's hospitals.
- To identify variations in treatment recommendations, admission criteria, and observation periods within these guidelines.
Main Methods:
- A survey was conducted among hospitals participating in the Pediatric Health Information System.
- Hospitals were queried for their most recent croup CPGs and any revisions.
- Data on treatment recommendations (e.g., racemic epinephrine use), observation times, and admission criteria were extracted and analyzed.
Main Results:
- Twenty out of thirty-eight (52.6%) responding hospitals had specific croup CPGs.
- Significant variation was observed in the number of racemic epinephrine doses recommended before admission (1-3 doses).
- Guidelines differed on indications for racemic epinephrine and recommended ED observation times, with most recommending less than 2 hours.
Conclusions:
- Substantial heterogeneity exists in current croup CPGs across children's hospitals.
- The findings underscore a need for developing standardized croup management protocols.
- Future standardization efforts could improve consistency and potentially optimize care for pediatric croup.
Background:
Croup is one of the most common respiratory complaints in pediatric emergency departments (EDs), yet little is known about clinical practice guidelines (CPGs) for this condition.
Objectives:
To describe variation in CPGs across US children's hospitals.
Methods:
We describe the prevalence and features of CPGs among hospitals that submit data to the Pediatric Health Information System. Each hospital was contacted between January 10, 2022, and April 25, 2022, for their most recent croup CPG and any revisions. Characteristics reported were based on the most recent CPG revision. Characteristics included treatment recommendations, utilization measures, ED observation times, and admission criteria. Interrater reliability between reviewers was reported as percentage agreement.
Results:
Thirty-eight hospitals (79.2%) responded to our query, of which 20 (52.6%) had croup CPGs. Interrater reliability was moderate-high for categorizing the indication for racemic epinephrine (RE) (19 of 20; 95%), the minimum number of RE doses recommended before admission (15 of 20; 75%), and ED observation time (19 of 20; 95%), and was 100% for all other characteristics. Three CPGs (15.0%) recommended 1 RE dose, 14 (70.0%) recommended 2 RE doses, and 3 (15.0%) recommended 3 RE doses before hospital admission. Thirteen (65%) CPGs recommended RE for stridor at rest, whereas 7 (30%) recommended RE for any degree of stridor. Fourteen (70%) CPGs recommended an ED observation time <2 hours, 3 (15%) recommended 2 to 4 hours, and 2 (10%) recommended >4 hours. Few CPGs (15%) recommended use of standardized croup clinical scores.
Conclusions:
Substantial variation exists among croup CPGs. Our results may inform future efforts to standardize croup CPGs across centers.
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