Related Experiment Video

Updated: Jul 19, 2025

Novel and Innovative Hybrid Technique for Type A Aortic Dissection
06:26

Novel and Innovative Hybrid Technique for Type A Aortic Dissection

Published on: March 28, 2025

386

Acute Myocardial Infarction Secondary to Triple Coronary Arteries Dissection in a Patient With Takayasu Vasculitis

Raad Tahtouh1, Khaled Al Khodari2, Jamila Al Ali Alhasan1

  • 1Internal Medicine Department, Hamad Medical Corporation, Doha, Qatar.

JACC. Case Reports
|August 7, 2023
PubMed

Insights

A rare case of spontaneous triple coronary artery dissection leading to myocardial infarction was observed in a young man. Further investigation revealed the underlying cause to be Takayasu arteritis, a condition not previously linked to this specific coronary event.

Area of Science:

  • Cardiology
  • Vascular Medicine
  • Rheumatology

Background:

  • Takayasu arteritis is a rare, large-vessel vasculitis primarily affecting the aorta and its branches.
  • Coronary artery dissection is an uncommon cause of myocardial infarction, particularly in young individuals.
  • Spontaneous coronary artery dissection (SCAD) is a known entity, but triple-vessel involvement is exceedingly rare.

Observation:

  • A young male patient presented with acute inferior wall myocardial infarction.
  • Cardiac imaging revealed spontaneous, synchronous dissection of all three major coronary arteries.
  • The patient had no typical risk factors for coronary artery disease.

Findings:

  • Further diagnostic workup confirmed the diagnosis of Takayasu arteritis.
  • The triple coronary artery dissection was directly attributed to the underlying vasculitis.
  • This represents the first reported instance of synchronous spontaneous triple coronary artery dissection associated with Takayasu arteritis.

Implications:

  • This case expands the known clinical manifestations of Takayasu arteritis.
  • It highlights the importance of considering vasculitis in young patients with spontaneous coronary artery dissection, even with multi-vessel involvement.
  • Early diagnosis and management of Takayasu arteritis are crucial to prevent severe cardiovascular events like myocardial infarction.

Keywords:
Takayasu arteritisacute coronary syndromemyocardial infarctionspontaneous coronary artery dissection

More Related Videos

Multimodality Diagnosis of Mesenteric Ischemia05:07

Multimodality Diagnosis of Mesenteric Ischemia

Published on: July 21, 2023

643
Direct Re-implantation of Left Coronary Artery into the Aorta in Adults with Anomalous Origin of Left Coronary Artery from the Pulmonary Artery ALCAPA13:10

Direct Re-implantation of Left Coronary Artery into the Aorta in Adults with Anomalous Origin of Left Coronary Artery from the Pulmonary Artery ALCAPA

Published on: April 24, 2017

18.6K

Related Concept Videos

Acute Coronary Syndrome III: Diagnostic Studies01:30

Acute Coronary Syndrome III: Diagnostic Studies

Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...
10
Acute Coronary Syndrome I: Introduction01:30

Acute Coronary Syndrome I: Introduction

Acute Coronary Syndrome (ACS) encompasses a spectrum of heart conditions caused by sudden obstruction of coronary arteries, typically resulting from the rupture of an atherosclerotic plaque and subsequent thrombus (blood clot) formation. This obstruction can lead to partial or complete blockage of blood flow, causing varying degrees of myocardial ischemia or infarction.ACS includes the following clinical entities:Unstable Angina (UA)Non-ST-Elevation Myocardial Infarction (NSTEMI)ST-Elevation...
30
Myocarditis III: Medical Management01:14

Myocarditis III: Medical Management

Myocarditis: Comprehensive Medical ManagementMyocarditis, the heart muscle inflammation, requires a comprehensive medical management strategy that addresses the underlying cause, provides supportive care, manages symptoms, and reduces cardiac workload.Infections and Autoimmune CausesAdminister appropriate antimicrobial therapy when an infectious agent causes myocarditis. For instance, penicillin treats infections caused by Group A Streptococcus. In cases where autoimmune processes are...
9
Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations01:19

Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations

The pathophysiology of Acute Coronary Syndrome [ACD] involves several key processes:The main underlying cause of ACD is atherosclerosis, a chronic inflammatory disease characterized by the buildup of lipid-laden plaques within the coronary arteries.As the atherosclerotic plaque grows in the coronary artery, it may become unstable due to the formation of a lipid-rich core and a thin fibrous cap. Inflammatory cells within the plaque, such as macrophages, secrete enzymes that degrade the...
20
Coronary Artery Disease III: Clinical Manifestations01:30

Coronary Artery Disease III: Clinical Manifestations

Coronary Artery Disease (CAD) is a primary health risk worldwide, leading to significant morbidity and mortality. The condition arises from the buildup of atherosclerotic plaques within the coronary arteries, resulting in diminished blood supply to the heart muscle.The clinical manifestations of CAD vary widely, from asymptomatic stages to severe, life-threatening conditions. Understanding these manifestations is crucial for early diagnosis and effective management.Angina Pectoris: The Warning...
13
Coronary Artery Disease II: Pathophysiology01:26

Coronary Artery Disease II: Pathophysiology

Coronary Artery Disease (CAD) originates from a series of events that impair the function of coronary arteries, the blood vessels responsible for delivering oxygen-rich blood to the heart muscle. The pathophysiology of CAD is closely linked to atherosclerosis, a chronic inflammatory and lipid-driven condition affecting the vascular endothelium.1. Endothelial DamageThe process begins with damage to the vascular endothelium, which serves as a protective barrier between the blood and the vessel...
12