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A Case of Father-Son Juvenile Acute Myocardial Infarction

Taiki Nishihara1, Yasuhiro Nagayoshi1, Naritsugu Sakaino1

  • 1Department of Cardiovascular Medicine, Faculty of Life Sciences, Graduate School of Medical Science, Kumamoto University, Kumamoto, Japan.

JACC. Case Reports
|August 7, 2023
PubMed

Insights

Coronary artery ectasia (CAE) can cause juvenile myocardial infarction. This report details a rare father-son case of myocardial infarction linked to CAE, highlighting potential familial links.

Area of Science:

  • Cardiology
  • Genetics
  • Pediatrics

Background:

  • Coronary artery ectasia (CAE) is a known cause of myocardial infarction in younger individuals.
  • Established causes of CAE include arteriosclerosis, vasculitis (e.g., Kawasaki disease), and genetic factors.
  • Familial aggregation of CAE-related juvenile myocardial infarction is infrequently reported.

Purpose of the Study:

  • To present an unusual case of juvenile myocardial infarction in a father and son attributed to coronary artery ectasia.
  • To contribute to the limited literature on familial aggregation of CAE-related myocardial infarction.

Main Methods:

  • Case report presentation.
  • Review of relevant medical literature.

Main Results:

  • An unusual instance of juvenile myocardial infarction in a father and son was identified.
  • The myocardial infarction in both individuals was associated with coronary artery ectasia.

Conclusions:

  • Coronary artery ectasia can manifest as juvenile myocardial infarction with familial clustering.
  • This case underscores the importance of considering genetic predisposition in unexplained juvenile myocardial infarction potentially linked to CAE.

Keywords:
coronary artery ectasiafamilial aggregationjuvenile myocardial infarction

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