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Machine Learning-Based Approach to Predict Intrauterine Growth Restriction.

Elham Taeidi1, Amene Ranjbar2, Farideh Montazeri1

  • 1Mother and Child Welfare Research Center, Hormozgan University of Medical Sciences, Bandar Abbas, IRN.

Cureus
|August 7, 2023
PubMed
Summary

Machine learning accurately predicts intrauterine growth restriction (IUGR). Deep learning models show the highest performance in identifying IUGR risk factors, aiding early intervention.

Keywords:
artificial intelligencedecision tree classificationdeep learningfetal growth restrictiongradient boost algorithmintrauterine growth restrictionintrauterine growth restriction (iugr)machine learningprenatal maternal screeningrandom forest

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Area of Science:

  • Maternal-fetal medicine
  • Artificial intelligence in healthcare
  • Predictive modeling in obstetrics

Background:

  • Intrauterine growth restriction (IUGR) poses significant risks to newborns.
  • Developing accurate prediction models for IUGR is crucial for timely intervention.
  • Machine learning offers a promising approach to integrate multiple risk factors for IUGR prediction.

Purpose of the Study:

  • To develop and evaluate machine learning models for predicting intrauterine growth restriction (IUGR).
  • To compare the performance of different machine learning algorithms in IUGR prediction.
  • To identify key risk factors contributing to IUGR based on model analysis.

Main Methods:

  • A cross-sectional study involving 8683 women was conducted.
  • Four machine learning algorithms were employed: Decision Tree, Random Forest, Deep Learning, and Gradient Boost.
  • Model performance was assessed using AUROC, accuracy, precision, and sensitivity.

Main Results:

  • The incidence of intrauterine growth restriction (IUGR) was 8.19%.
  • Deep Learning demonstrated the highest predictive performance with an AUROC of 0.91.
  • Key predictors identified included drug addiction, prior IUGR, chronic hypertension, preeclampsia, anemia, and COVID-19.

Conclusions:

  • Machine learning models are effective for predicting intrauterine growth restriction (IUGR).
  • The Deep Learning algorithm provides a highly accurate method for IUGR prediction.
  • Identifying high-risk pregnancies through advanced modeling can improve perinatal outcomes.