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Prevalence of Glaucoma Following Paediatric Cataract Surgery in an Australian Tertiary Referral Centre
Alanna Wood1,2, Benjamin Lim2, Jim Matthews3
1Save Sight Institute, Discipline of Clinical Ophthalmology and Eye Health, Faculty of Medicine and Health, Sydney, NSW, Australia.
Insights
Secondary glaucoma is a common complication after childhood cataract surgery. Microcornea was identified as a significant risk factor for developing this condition in pediatric patients.
Area of Science:
- Ophthalmology
- Pediatric Ophthalmology
- Glaucoma Research
Background:
- Secondary glaucoma is the most frequent complication following pediatric cataract surgery.
- Understanding its incidence and risk factors is crucial for managing long-term outcomes in children.
Purpose of the Study:
- To determine the incidence of secondary glaucoma after childhood cataract surgery.
- To identify the time to progression and associated risk factors for secondary glaucoma in pediatric patients.
- To analyze outcomes including glaucoma development and time to onset post-surgery.
Main Methods:
- A retrospective case series was conducted from 2003-2017 at a tertiary children's hospital.
- Included patients were 16 years or younger undergoing congenital cataract extraction.
- Multivariate Cox Regression analysis was used to identify risk factors.
Main Results:
- Secondary glaucoma developed in 11.9% of eyes studied (320 eyes in 216 patients).
- The average time to onset of secondary glaucoma was 3.2 years post-surgery.
- Microcornea was the only factor significantly associated with increased secondary glaucoma risk (HR 6.30, p=0.003).
Conclusions:
- Glaucoma remains a significant long-term complication in children after cataract surgery.
- Early identification and monitoring of risk factors like microcornea are essential.
- Despite advancements, proactive management is key to mitigating this complication.
Purpose:
Secondary glaucoma following childhood cataract surgery remains the most common complication in the paediatric population. This study aimed to determine the incidence, time to progression and risk factors associated with the development of secondary glaucoma following childhood cataract surgery in a paediatric population. Outcome measures were the detection of secondary glaucoma, postoperative time frame to development of glaucoma and risk factors in its development.
Patients And Methods:
A retrospective case series was conducted between 2003 and 2017 at a tertiary children's hospital in Sydney. The patient population included those 16 years or less of age who underwent congenital cataract extraction, with or without an intraocular lens implantation and who had been followed up for a minimum of six months following surgery. Patients were excluded if they had cataract aetiology other than congenital idiopathic cataract. Multivariate Cox Regression analysis was used to determine relevant risk factors.
Results:
A total of 320 eyes in 216 patients were included in the study. Secondary glaucoma developed in 11.9% of eyes. In those that developed secondary glaucoma, the average time to onset from surgery was 3.2 years (median 2.75 years). The mean age of diagnosis of secondary glaucoma was 4.58 years (median 3.5 years, range 2.5 months to 13.23 years). Microcornea was the only adverse characteristic significantly associated with an increased risk of secondary glaucoma (HR 6.30, p 0.003).
Conclusion:
Despite modern surgical techniques, glaucoma remains a significant long-term sequela in children following cataract surgery.
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