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Stem Cell Therapy for Tissue Regeneration

Stem Cell Therapy for Tissue Regeneration

Stem cell therapy is a method used in regenerative medicine to repair and restore function to damaged tissues and organs. Stem cells have the potential to proliferate and differentiate into various tissue types, making them ideal candidates for tissue regeneration. For example, hematopoietic stem cell transplants are commonly used in blood cancer treatment to replenish damaged bone marrow and restore healthy blood cells.
Types of Stem Cells used in Stem Cell Therapy
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Related Experiment Video

Updated: Jul 19, 2025

Isolation of Mesenchymal Stem Cells from Human Alveolar Periosteum and Effects of Vitamin D on Osteogenic Activity of Periosteum-derived Cells

Isolation of Mesenchymal Stem Cells from Human Alveolar Periosteum and Effects of Vitamin D on Osteogenic Activity of Periosteum-derived Cells

Published on: May 4, 2018

Tooth-derived stem cells integrated biomaterials for bone and dental tissue engineering.

Selvaraj Vimalraj¹, Sekaran Saravanan²

¹Department of Prosthodontics, Saveetha Dental College and Hospital, Saveetha Institute of Medical and Technical Sciences (SIMATS), Saveetha University, Chennai, 600 077, Tamil Nadu, India. vimalr50@gmail.com.

Cell and Tissue Research

|August 7, 2023

Summary

Tissue engineering utilizes biomaterials to deliver stem cells for tissue regeneration. Tooth-derived mesenchymal stem cells (MSCs) offer a promising source for these regenerative therapies.

Keywords:

Biomaterials Dental mesenchymal stem cells Dental pulp stem cells Tissue engineering

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Area of Science:

Biomaterials Science
Regenerative Medicine
Stem Cell Biology

Background:

Tissue engineering strategies are emerging to address limitations in conventional medical treatments.
Biomaterials serve as scaffolds, delivering cells and bioactive substances or attracting endogenous cells for tissue formation.
Teeth represent an abundant source of multipotent mesenchymal stem cells (MSCs) with significant regenerative potential.

Purpose of the Study:

To review recent advancements and promising directions in cell transplantation and homing techniques.
To explore the use of dental MSCs for tissue regeneration applications.
To provide an overview of current approaches combining tooth-derived MSCs, biomaterials, and bioactive substances.

Main Methods:

Literature review of recent advancements in tissue engineering and stem cell therapy.
Analysis of cell transplantation and homing techniques utilizing dental MSCs.
Synthesis of current research on biomaterial and bioactive substance integration with dental MSCs.

Main Results:

Dental MSCs are a viable and abundant source for regenerative medicine.
Biomaterials can be engineered to support cell behavior and tissue formation.
Effective cell delivery and homing strategies are crucial for successful regeneration.

Conclusions:

Tooth-derived MSCs hold significant promise for various tissue regeneration applications.
The combination of biomaterials, bioactive substances, and dental MSCs represents a key frontier in regenerative medicine.
Further research into cell transplantation and homing techniques will enhance the efficacy of these therapies.