Crystal structure of Prp16 in complex with ADP

Tim Benedict Garbers1, Marieke Enders1, Piotr Neumann1

  • 1Department of Molecular Structural Biology, Institute of Microbiology and Genetics, GZMB, Georg-August-University Göttingen, Göttingen, Germany.

Summary

This study presents the first crystal structure of the DEAH-box helicase Prp16 bound to ADP. This provides new insights into spliceosome remodeling and RNA splicing quality control mechanisms.

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