An automatic stimulus generation system for electroretinogram capture and processing

An automated system is presented for on-line capture and processing of the analog signal obtained in response to light or X-ray stimulation of isolated rat retina maintained in survival by perfusion. The most important part of the system is a microcomputer Apple II (48 K Europlus) equipped with interface boards. Basic and assembler programs automatically deliver light or X-ray stimulation every 5 min. Data capture and data processing are carried out following each retinal response. Calculated parameters of the ERG, and 200 values obtained after sampling of an ERG are placed in a data file on a floppy disc. One hundred ERGs can be stored in this way.