Dietary, Herbal and Nutritional Interventions for Managing Rheumatoid Arthritis: A Review

Aanchal Verma1, Nandini Dubey1, Anant Agrawal1

  • 1Department of Pharmacology, Institute of Pharmaceutical Research, GLA University, Mathura, Uttar Pradesh, India.

Insights

Natural compounds and supplements show promise in managing rheumatoid arthritis (RA) symptoms. These dietary and herbal interventions offer anti-inflammatory and bone-protective benefits, potentially reducing reliance on conventional drugs.

Area of Science:

  • Immunology
  • Rheumatology
  • Nutritional Science

Background:

  • Rheumatoid arthritis (RA) is a systemic inflammatory condition causing joint damage.
  • Genetic and environmental factors influence RA susceptibility.
  • Current treatments for RA may have adverse effects, driving research into natural alternatives.

Purpose of the Study:

  • To review the anti-inflammatory, antioxidant, analgesic, immunomodulatory, and bone erosion-preventing properties of natural compounds.
  • To compile evidence on nutritional and herbal supplements for managing RA symptoms.
  • To explore natural ingredients that may improve overall health and reduce RA risk.

Main Methods:

  • Literature review of studies on natural compounds and rheumatoid arthritis.
  • Analysis of research on dietary components, phenolic substances, spices (ginger, turmeric), vitamins, and probiotics.
  • Evaluation of evidence for anti-inflammatory and disease-modifying effects.

Main Results:

  • Nutritional and herbal supplements demonstrate potential as adjunctive therapies for RA.
  • Various natural ingredients influence inflammatory pathways involved in RA pathophysiology.
  • Reported benefits include anti-inflammatory, antioxidant, analgesic, immunomodulatory, and bone protection effects.

Conclusions:

  • Natural compounds, including dietary and herbal supplements, show significant potential in managing rheumatoid arthritis.
  • These natural interventions may help alleviate RA symptoms and slow disease progression.
  • Focus on natural ingredients offers a promising avenue for enhancing well-being and reducing RA risk.

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