Swedish obstetric thromboprophylaxis guideline: background and update

Area of Science:

• Obstetrics and Gynecology
• Hematology
• Public Health

Background:

• Venous thromboembolism (VTE) risk assessment and prophylaxis are standard in pregnancy.
• Swedish obstetricians have utilized a weighted-risk algorithm for VTE risk estimation for two decades.

Purpose of the Study:

• To present the latest update of the Swedish VTE risk algorithm for obstetric patients.
• To detail the algorithm's basis, application in assessing moderate-to-high risk, and efficacy.
• To describe associated lifestyle advice for pregnant individuals.

Main Methods:

• A weighted-risk algorithm based on factors conferring a fivefold or greater VTE risk.
• Risk assessment defines patients requiring thromboprophylaxis based on absolute risk thresholds.
• Efficacy data and patient lifestyle advice are presented.

Main Results:

• The algorithm identifies pregnant women at moderate-to-high risk for VTE.
• It guides patient selection, timing, duration, and dosage of thromboprophylaxis.
• The guideline is user-friendly and aids in minimizing treatment disparities.

Conclusions:

• The updated Swedish guideline provides an effective and practical approach to obstetric VTE risk management.
• It facilitates accurate identification of high-risk individuals, optimizing thromboprophylaxis.
• This strategy helps reduce the risks of both under- and overtreatment in pregnant populations.