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Keratoconus in Thai population - a cross-sectional hospital-based study
Yonrawee Piyacomn1, Ngamjit Kasetsuwan1, Vilavun Puangsricharern1
1Department of Ophthalmology, Excellence Center for Cornea and Limbal Stem Cell Transplantation, King Chulalongkorn Memorial Hospital, Faculty of Medicine, Chulalongkorn University, Bangkok 10330, Thailand.
Asian Biomedicine : Research, Reviews and News
|August 8, 2023
Summary
This study found a 1.66% prevalence of keratoconus among Thai patients seeking refractive surgery. Most affected individuals were male, presenting with mild, bilateral keratoconus in their early twenties.
Area of Science:
- Ophthalmology
- Epidemiology
- Corneal Diseases
Background:
- Limited epidemiological data exists for keratoconus in Southeast Asia.
- A study in Thailand is crucial for understanding keratoconus prevalence and impact in the region.
Purpose of the Study:
- To determine the prevalence of keratoconus in Thai patients undergoing refractive surgery.
- To analyze the clinical and topographical characteristics of keratoconus in this population.
Main Methods:
- Retrospective review of medical records from April 2015 to August 2018.
- Calculation of keratoconus and suspect prevalence among patients seeking laser vision correction.
- Classification of keratoconus stages (Amsler-Krumeich) and cone types (topography).
Main Results:
- Keratoconus and suspect prevalence were 1.66% and 0.68%, respectively.
- The majority of keratoconus patients (73.8%) were male, with a mean age at diagnosis of 25.25 years.
- Stage 1 keratoconus was most common (39%), with oval cones (57%) predominating topographically.
Conclusions:
- Keratoconus affects 1.66% of Thai patients seeking refractive surgery.
- The disease typically presents in males during their second decade, often in a mild, bilateral stage.
- Understanding these characteristics aids in early detection and management strategies.

