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Updated: Jul 19, 2025

High-throughput Physical Mapping of Chromosomes using Automated in situ Hybridization
Published on: June 28, 2012
Genome Report: chromosome-scale genome assembly of the African spiny mouse (Acomys cahirinus)
Elizabeth Dong Nguyen1,2,3, Vahid Nikoonejad Fard4, Bernard Y Kim5
1Department of Pediatrics, University of Washington, Seattle, WA 98195, USA.
Abstract:
There is increasing interest in the African spiny mouse (Acomys cahirinus) as a model organism because of its ability for regeneration of tissue after injury in skin, muscle, and internal organs such as the kidneys. A high-quality reference genome is needed to better understand these regenerative properties at the molecular level. Here, we present an improved reference genome for A. cahirinus generated from long Nanopore sequencing reads. We confirm the quality of our annotations using RNA sequencing data from 4 different tissues. Our genome is of higher contiguity and quality than previously reported genomes from this species and will facilitate ongoing efforts to better understand the regenerative properties of this organism.
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