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Published on: February 4, 2018
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Lyme neuroborreliosis: A case report
Babak Sayad1, Arefeh Babazadeh2, Mohammad Barary3
1Clinical Research Development Center, Imam Reza Hospital Kermanshah University of Medical Sciences Kermanshah Iran.
Clinical Case Reports
|August 9, 2023
Summary
This case highlights Lyme neuroborreliosis, a nervous system complication of Lyme disease. Early antibiotic treatment, like ceftriaxone, is crucial for managing neurological symptoms and achieving patient recovery.
Area of Science:
- Neurology
- Infectious Diseases
- Neuroimmunology
Background:
- Lyme neuroborreliosis (LNB) is a significant manifestation of Lyme borreliosis, affecting the central and peripheral nervous systems.
- Diagnosis of LNB can be challenging due to diverse neurological and psychiatric presentations.
- Prompt antibiotic intervention is key to successful LNB management.
Observation:
- A 55-year-old male presented with sudden tonic-clonic seizures.
- Cerebrospinal fluid analysis revealed pleocytosis (380 WBC/mL) and elevated protein, with normal glucose.
- Serological tests confirmed IgG and IgM antibodies to Borrelia burgdorferi.
Findings:
- The patient's seizures and neurological status significantly improved after intravenous ceftriaxone administration.
- Wright and 2-mercaptoethanol tests were favorable, supporting the diagnosis.
- This case underscores the importance of considering LNB in patients with unexplained neurological symptoms.
Implications:
- Early diagnosis and treatment of LNB are critical for preventing long-term neurological sequelae.
- This case emphasizes the effectiveness of ceftriaxone in treating neuroborreliosis.
- Increased awareness among clinicians is necessary for timely recognition and management of LNB.
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