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Updated: Jul 19, 2025

Dorsal Root Ganglion Injection and Dorsal Root Crush Injury as a Model for Sensory Axon Regeneration
Published on: May 3, 2017
Twiddler's syndrome after dorsal root ganglion stimulation: A case report
Maarten Vanloon1, Vincent Raymaekers2,3,4, Sacha Meeuws5,6
1Faculty of Health, Medicine and Life Sciences, Maastricht University, the Netherlands.
Abstract:
Dorsal root ganglion stimulation (DRG-S) is a promising therapy for chronic neuropathic pain, but complications of this therapy are poorly understood. Twiddler's syndrome, a rare complication characterized by lead displacement and coiling of wires, has been reported in other neuromodulation devices, but has not been described in the context of DRG-S. Here, we present a first-of-a-kind case report of Twiddler's syndrome occurring after 8 months of DRG-S. This case report highlights the importance of considering Twiddler's syndrome as a potential complication in patients undergoing DRG-S, especially in those with significant weight loss history.

