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Discovery of New Intracellular Pathogens by Amoebal Coculture and Amoebal Enrichment Approaches
Published on: October 27, 2013
A primary amoebic meningoencephalitis case associated with swimming in seawater
Feng Wang1, Fuping Shen2, Wenchu Dai3
1Department of Laboratory Medicine, The First Affiliated Hospital of Ningbo University, Ningbo University, Ningbo, China.
Abstract:
This case report describes a 62-year-old male fisherman who presented with persistent vomiting, headache, and behavior changes. Despite initial antibiotic and corticosteroid treatment, his condition worsened, leading to coma and subsequent death. Macro-genome sequencing of cerebrospinal fluid (CSF) revealed the presence of Naegleria fowleri infection, which had been missed during initial laboratory tests. The patient's exposure history included sea-swimming near Zhoushan Island.
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