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Murine Ileocolic Bowel Resection with Primary Anastomosis
08:49

Murine Ileocolic Bowel Resection with Primary Anastomosis

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[A case of ulcerative colitis complicated by disseminated intravascular coagulation that improved markedly after

Mizuki Tatsuno1, Kazutaka Koganei1, Kenji Tatsumi1

  • 1Department of Inflammatory Bowel Disease, Yokohama Municipal Citizen's Hospital.

Nihon Shokakibyo Gakkai Zasshi = the Japanese Journal of Gastro-Enterology
|August 9, 2023
PubMed

Insights

Severe ulcerative colitis (UC) complicated by disseminated intravascular coagulation (DIC) in a 57-year-old man resolved after surgical intervention. Prompt total proctocolectomy effectively treated the DIC when medical management failed, highlighting surgery as a crucial option.

Area of Science:

  • Gastroenterology and Surgery
  • Hematology and Coagulation Disorders

Background:

  • Severe ulcerative colitis (UC) can present with life-threatening complications.
  • Disseminated intravascular coagulation (DIC) is a rare but serious complication of UC.
  • Medical management of DIC associated with UC may have limited efficacy.

Observation:

  • A 57-year-old male patient with severe UC developed DIC.
  • Initial medical treatments failed to improve the patient's coagulopathy.
  • The patient underwent total proctocolectomy with ileoanal anastomosis and ileostomy.

Findings:

  • Post-surgery, the patient's platelet count and coagulability rapidly improved.
  • The patient achieved complete recovery from disseminated intravascular coagulation.
  • Surgical intervention successfully addressed the underlying cause of DIC.

Implications:

  • Surgical management should be considered for UC-induced DIC refractory to medical therapy.
  • Early surgical intervention can be life-saving in complex UC cases with DIC.
  • This case underscores the importance of a multidisciplinary approach in managing severe gastrointestinal and hematological emergencies.

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