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Dissecting human population variation in single-cell responses to SARS-CoV-2

Yann Aquino1,2, Aurélie Bisiaux1, Zhi Li1

  • 1Human Evolutionary Genetics Unit, Institut Pasteur, Université Paris Cité, CNRS UMR2000, Paris, France.

Nature
|August 9, 2023
PubMed
Summary

SARS-CoV-2 triggers weaker, more varied immune responses than influenza, with population differences influenced by genetics and cell composition. Natural selection and Neanderthal DNA also shape these diverse immune reactions to viruses.

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