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Extraskeletal mesenchymal chondrosarcoma arising from soft tissues: A rare case report
Razieh Shahnazari1, Fatemeh Montazer2, Shahriar Shirzadi3
1Radiology Department of Iran University of Medical Sciences (IUMS), Tehran, Iran.
Cancer Reports (Hoboken, N.J.)
|August 9, 2023
Summary
Extraskeletal mesenchymal chondrosarcoma (EMCS) is a rare cancer. Accurate diagnosis requires meticulous pathological and imaging investigations due to its rarity and lack of guidelines.
Area of Science:
- Oncology
- Pathology
- Radiology
Background:
- Chondrosarcomas are rare cancers, with mesenchymal subtypes being even rarer.
- Extraskeletal mesenchymal chondrosarcoma (EMCS) accounts for a small fraction of these rare tumors, typically occurring outside of bone.
- Diagnosis is challenging due to rarity and lack of established guidelines.
Observation:
- A 38-year-old woman presented with right breast pain and a palpable mass.
- Radiological evaluation indicated a tumor outside breast tissue and not connected to bone.
- Pathological evaluation revealed biphasic morphology, confirmed by immunohistochemistry as EMCS.
Findings:
- The case confirms EMCS in an extraskeletal location, specifically the breast region.
- Biphasic morphology and immunohistochemistry were crucial for accurate diagnosis.
- Surgical removal followed by chemotherapy was the treatment approach.
Implications:
- Accurate diagnosis of EMCS necessitates precise pathological and imaging studies.
- Meticulous sampling is vital for correct diagnosis of rare tumors like EMCS.
- Further research may elucidate optimal diagnostic and treatment strategies for EMCS.
