Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Overview of Synapses01:25

Overview of Synapses

2.4K
A synapse is a specialized structure where two neurons connect, allowing them to pass an electrical or chemical signal to another neuron. It is the point of communication between neurons. The term "synapse" is derived from the Greek word "synapsis," which means "conjunction." The entire process of neural communication revolves around the synapse. When activated, a neuron releases chemicals known as neurotransmitters into the synapse. These neurotransmitters cross the synapse and bind to...
2.4K
Neuron Structure01:31

Neuron Structure

223.4K
Overview
223.4K
Electrical Synapses01:28

Electrical Synapses

8.4K
Electrical synapses found in all nervous systems play important and unique roles. In these synapses, the presynaptic and postsynaptic membranes are very close together (3.5 nm) and are actually physically connected by channel proteins forming gap junctions.
Gap junctions allow the current to pass directly from one cell to the next. In contrast, in the chemical synapse, the neurotransmitters carry the information through the synaptic cleft from one neuron to the next. They consist of two...
8.4K
Chemical Synapses01:26

Chemical Synapses

2.6K
Chemical synapses are specialized sites between two neurons or between a neuron and a non-neuronal cell like a muscle, glandular or sensory cell.
Because chemical synapses depend on the release of neurotransmitter molecules from synaptic vesicles to pass on their signal, there is an approximately one millisecond delay between when the axon potential reaches the presynaptic terminal and when the neurotransmitter leads to opening of postsynaptic ion channels. Additionally, this signaling is...
2.6K
The Synapse02:47

The Synapse

125.7K
Neurons communicate with one another by passing on their electrical signals to other neurons. A synapse is the location where two neurons meet to exchange signals. At the synapse, the neuron that sends the signal is called the presynaptic cell, while the neuron that receives the message is called the postsynaptic cell. Note that most neurons can be both presynaptic and postsynaptic, as they both transmit and receive information.
125.7K
Synaptic Signaling01:09

Synaptic Signaling

5.6K
Neurons communicate at synapses, or junctions, to excite or inhibit the activity of other neurons or target cells, such as muscles. Synapses may be chemical or electrical.
Most synapses are chemical, meaning an electrical impulse or action potential spurs the release of chemical messengers called neurotransmitters. The neuron sending the signal is called the presynaptic neuron, and the neuron receiving the signal is the postsynaptic neuron.
The presynaptic neuron fires an action potential that...
5.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Placozoan secretory cell types implicated in feeding, innate immunity and regulation of behavior.

PloS one·2025
Same author

Paraoxonase-1 Is a Pivotal Regulator Responsible for Suppressing Allergic Airway Inflammation Through Adipose Stem Cell-Derived Extracellular Vesicles.

International journal of molecular sciences·2024
Same author

Immunomodulatory Effect of Adipose Stem Cell-Derived Extra-Cellular Vesicles on Cytokine Expression and Regulatory T Cells in Patients with Asthma.

International journal of molecular sciences·2024
Same author

Placozoan secretory cell types implicated in feeding, innate immunity and regulation of behavior.

bioRxiv : the preprint server for biology·2024
Same author

A Novel Fabrication of Heterogeneous Saponified Poly(Vinyl Alcohol)/Pullulan Blend Film for Improved Wound Healing Application.

International journal of molecular sciences·2024
Same author

Airway leakage due to malpositioning of esophageal temperature probe during robot-assisted radical prostatectomy: a case report.

The Journal of international medical research·2024
Same journal

Calcium at the crossroads of the immunometabolic signaling and comorbidity in schizophrenia.

Frontiers in synaptic neuroscience·2026
Same journal

Mechanistic insights into the synaptic damage-repair and regeneration processes in neurodegenerative Alzheimer's disease: phytochemicals as neuroprotective agents.

Frontiers in synaptic neuroscience·2026
Same journal

NMDA receptors play an important role in postictal potentiation in immature rats.

Frontiers in synaptic neuroscience·2026
Same journal

Suicidality as a potential risk and therapeutic target during widespread GLP-1 receptor agonists use: implications of inflammation.

Frontiers in synaptic neuroscience·2026
Same journal

NMDA receptor mediated tonic excitatory currents are elicited by EAAT inhibition on human neocortical pyramidal neurons.

Frontiers in synaptic neuroscience·2026
Same journal

Automated ROI detection allows rapid quantification of synaptic activity across tens of thousands of synapses in cell culture.

Frontiers in synaptic neuroscience·2026
See all related articles

Related Experiment Video

Updated: Jul 19, 2025

3D Modeling of Dendritic Spines with Synaptic Plasticity
07:13

3D Modeling of Dendritic Spines with Synaptic Plasticity

Published on: May 18, 2020

6.9K

Editorial: Structural and quantitative modeling of synapses

Jae Hoon Jung1, Noreen E Reist2, Sebastian Doniach3,4

  • 1Laboratory of Neurobiology, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, United States.

Frontiers in Synaptic Neuroscience
|August 10, 2023
PubMed
Summary

No abstract available in PubMed .

Keywords:
active zoneelectron microscopylight microscopypostsynaptic densitysegmentationsimulationsynapsesynaptic transmission

More Related Videos

Evaluation of Synapse Density in Hippocampal Rodent Brain Slices
07:44

Evaluation of Synapse Density in Hippocampal Rodent Brain Slices

Published on: October 6, 2017

17.2K
Quantifying Synapses: an Immunocytochemistry-based Assay to Quantify Synapse Number
18:11

Quantifying Synapses: an Immunocytochemistry-based Assay to Quantify Synapse Number

Published on: November 16, 2010

35.9K

Related Experiment Videos

Last Updated: Jul 19, 2025

3D Modeling of Dendritic Spines with Synaptic Plasticity
07:13

3D Modeling of Dendritic Spines with Synaptic Plasticity

Published on: May 18, 2020

6.9K
Evaluation of Synapse Density in Hippocampal Rodent Brain Slices
07:44

Evaluation of Synapse Density in Hippocampal Rodent Brain Slices

Published on: October 6, 2017

17.2K
Quantifying Synapses: an Immunocytochemistry-based Assay to Quantify Synapse Number
18:11

Quantifying Synapses: an Immunocytochemistry-based Assay to Quantify Synapse Number

Published on: November 16, 2010

35.9K