Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Levamisole therapy under different dermatological indications].

E Haneke

    Zeitschrift Fur Hautkrankheiten
    |May 1, 1979
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Zigzag longitudinal melanonychia: a peculiar dermoscopic pattern.

    Journal of the European Academy of Dermatology and Venereology : JEADV·2020
    Same author

    Melanoma of the nail apparatus: a systematic review and meta-analysis of current challenges and prognosis.

    Journal of the European Academy of Dermatology and Venereology : JEADV·2019
    Same author

    Topical steroids for the treatment of retronychia.

    Journal of the European Academy of Dermatology and Venereology : JEADV·2019
    Same author

    Subungual metastasis: expanding the spectrum.

    Journal of the European Academy of Dermatology and Venereology : JEADV·2019
    Same author

    Review of a recently delineated longitudinal lesion of the nail: onychopapilloma.

    Journal of the European Academy of Dermatology and Venereology : JEADV·2018
    Same author

    Verrucous epidermal naevus: a misleading diagnosis for 28 years.

    Journal of the European Academy of Dermatology and Venereology : JEADV·2017

    Levamisole immunostimulation significantly improved recurrent herpes simplex infections in many patients. It also reduced recurrence frequency for genital herpes and decreased aphthae frequency and pain.

    Area of Science:

    • Immunology
    • Dermatology
    • Infectious Diseases

    Background:

    • Recurrent viral and fungal infections pose significant clinical challenges.
    • Immunostimulatory agents are explored for managing chronic and recurrent conditions.

    Purpose of the Study:

    • To evaluate the efficacy of levamisole in treating patients with recurrent herpes simplex infections, aphthae, and other conditions.
    • To assess the safety and side effect profile of levamisole in a clinical setting.

    Main Methods:

    • Statistical evaluation of treatment outcomes in 128 patients who received levamisole for immunostimulation.
    • Observation of recurrence frequency, symptom severity, and side effects.

    Main Results:

    • Highly significant improvement observed in 44 patients with recurrent herpes simplex labialis, facialis, and oralis.

    Related Experiment Videos

  • Reduced recurrence frequency noted in 14 patients with recurrent herpes genitalis, lumbalis, and glutaealis.
  • Decreased frequency and pain associated with aphthae in 16 subjects.

    • Conclusions:

    • Levamisole demonstrates significant efficacy in managing certain recurrent herpes simplex infections and aphthae.
    • Consideration of levamisole is warranted for recalcitrant chronic candidoses and antibiotic-resistant bacterial infections.
    • Levamisole is generally well-tolerated, with slight side effects being common but severe ones rare.