Related Experiment Video
Updated: Jul 19, 2025

Intracoronary Acetylcholine Provocation Testing for Assessment of Coronary Vasomotor Disorders
Published on: August 18, 2016
[Coronary anaphylaxis or Kounis syndrome]
Jean-Baptiste Bouillon-Minois1, François Saget2, Nicolas Peschanski2,3
1Pôle Urgences, CHU Clermont-Ferrand, France.
Kounis syndrome, a rare cause of anaphylaxis, mimics acute coronary syndrome and carries a high mortality risk. This case highlights a patient experiencing Kounis syndrome after amoxicillin ingestion.
Area of Science:
- Cardiology
- Allergy and Immunology
- Pharmacology
Background:
- Kounis syndrome is a rare but serious condition where acute coronary syndromes are precipitated by allergic reactions.
- It accounts for 3.4% of anaphylactic reactions and has a significant mortality rate of 7%.
- The clinical presentation often mimics classic acute coronary syndrome, leading to diagnostic challenges.
Related Concept Videos
Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations
Acute Coronary Syndrome I: Introduction
Allergic Reactions
Coronary Artery Disease III: Clinical Manifestations
Acute Coronary Syndrome V: Nursing Management
Acute Coronary Syndrome III: Diagnostic Studies

