Redefining Cancer Research Priorities in Low- and Middle-Income Countries in the Post-COVID-19 Global Context: A...

Area of Science:

• Global Health
• Oncology
• Health Systems Research

Background:

• Post-COVID-19 funding for cancer research is challenging, especially in resource-challenged regions (RCRs).
• Limited research ecosystems in RCRs necessitate targeted research priorities.
• Identifying priorities requires input from both researchers and patients.

Purpose of the Study:

• To establish a prioritized list of cancer research areas for countries with limited resources.
• To inform strategic cancer research investments in low- and middle-income countries.
• To align research efforts with the needs of patients and healthcare systems in RCRs.

Main Methods:

• A modified Delphi survey was conducted with 151 cancer experts from low- and middle-income countries.
• Two rounds of surveys assessed the importance of predetermined and suggested research priorities.
• A forced-choice ranking exercise and composite voting scores (T-scores) determined the final priority list.

Main Results:

• The top priority was adapting treatment guidelines and strategies to available resources (T=83).
• Other key priorities included cancer registries (T=62), prevention (T=52), end-of-life care (T=53), and affordable care (T=51).
• For COVID-19/cancer research, priorities included post-pandemic maintenance of strategies (T=36) and pandemic preparedness (T=18).

Conclusions:

• Strategic cancer research priorities in RCRs involve adaptive treatment guidelines and sustainable registries.
• Prevention, value-based care, research capacity building, and addressing inequities are crucial.
• Research should focus on local risk factors and equitable access to care and prevention.