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Determining patient value profiles in psoriasis.

N T Hilhorst1,2, E Abatih3, E Deprez1,2

  • 1Dermatology Research Unit, Ghent University, Ghent, Belgium.

Experimental Dermatology
|August 11, 2023
PubMed
Summary
This summary is machine-generated.

This study identified three distinct patient value profiles for psoriasis patients, enabling healthcare professionals to tailor treatments for better outcomes and value. These profiles help guide psoriasis management for a more goal-oriented approach.

Keywords:
outcomespsoriasisvalue

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Area of Science:

  • Dermatology
  • Health Economics
  • Patient-Reported Outcomes

Background:

  • Healthcare professionals (HCPs) aim to maximize patient value, defined as health outcomes relative to costs.
  • Identifying individual patient-relevant outcomes in psoriasis remains a challenge.

Purpose of the Study:

  • To define distinct 'patient value profiles' within a psoriasis cohort.
  • To enable translation of these profiles into daily practice for enhanced individual patient value.

Main Methods:

  • Hierarchical clustering on principal components (HCPC) was used to group patients with similar outcome rankings.
  • A multi-class decision tree (MDT) was developed to assign patients to identified clusters using socio-demographic and clinical data.

Main Results:

  • 120 psoriasis patients participated; median age 50, 36.7% female, median PASI 2.4, median disease duration 17 years.
  • Three distinct patient value profiles were identified: Quality of Life (QoL), cost, and treatment.
  • The developed MDT achieved a 64% accuracy in assigning patients to these profiles.

Conclusions:

  • Three distinct patient value profiles were identified in the psoriasis cohort.
  • A MDT facilitates easy patient assignment to these profiles.
  • HCPs can utilize these profiles to personalize psoriasis management for a more goal-directed approach.