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Progressive multifocal leukoencephalopathy in an HIV patient: A case report and literature review

Ting Lei1, Ai Deng1, Lianchi Li2

  • 1Center of Infectious Diseases, West China Hospital Sichuan University Chengdu China.

Clinical Case Reports
|August 11, 2023
PubMed

Insights

Progressive multifocal leukoencephalopathy (PML), a brain infection from JC virus reactivation, can occur in HIV patients. Early MRI detection of white-matter lesions is crucial for diagnosis and management.

Area of Science:

  • Neuroscience
  • Infectious Diseases
  • Virology

Background:

  • Progressive multifocal leukoencephalopathy (PML) is a rare, opportunistic brain infection.
  • It is caused by the John Cunningham virus (JCV), leading to oligodendrocyte lysis.
  • PML is particularly associated with conditions that compromise the immune system, such as HIV/AIDS.
Keywords:
HIVJohn Cunningham virusnext‐generation sequencingprogressive multifocal leukoencephalopathy

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