Lipoinjection with Adipose Stem Cells for Nasal Modeling: Rhino Cell, a Highly Versatile Alternative

Area of Science:

• Regenerative Medicine
• Plastic and Reconstructive Surgery
• Aesthetic Dermatology

Background:

• Growing patient demand for non-surgical facial aesthetic procedures.
• Autologous fat grafting as a viable option for facial contouring.
• Limitations of traditional fat grafting and the potential of stem cell enrichment.

Purpose of the Study:

• To describe an innovative technique for nonsurgical nasal modeling using micrografts enriched with adipose-derived mesenchymal stem cells (ASCs).
• To evaluate the feasibility and potential of this ASC-enriched fat lipoinjection for nasal augmentation.

Main Methods:

• Fat tissue was collected and processed into nanofat (for ASC isolation) and microfat.
• Microfat was enriched with isolated ASCs.
• Lipoinjection of ASC-enriched microfat was performed in the supraperiosteal plane on the nasal dorsum and via retrolabial access for the nasal tip and columella base.

Main Results:

• The described technique offers a novel approach to nasal reshaping using autologous fat enriched with ASCs.
• The procedure allows for targeted lipoinjection in specific nasal areas.
• Potential for a minimally invasive procedure with rapid patient recovery.

Conclusions:

• Nonsurgical nasal modeling using ASC-enriched micrografts presents an attractive and innovative alternative.
• This technique is not a replacement for surgical rhinoplasty but offers a less invasive option.
• The procedure allows for quick recovery and potential for repetition if needed.