Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Efficacy of isolated profundaplasty.

A M Graham, B L Gewertz, C K Zarins

    Canadian Journal of Surgery. Journal Canadien De Chirurgie
    |September 1, 1986
    PubMed
    Summary

    Profundaplasty effectively treats aortofemoral graft failure but is not recommended for isolated limb salvage. Angiographic criteria failed to reliably predict success in patients undergoing profundaplasty alone.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Failure to rescue the elderly: a superior quality metric for trauma centers.

    European journal of trauma and emergency surgery : official publication of the European Trauma Society·2017
    Same author

    Effect of rifampin on the pharmacokinetics, safety and tolerability of navitoclax (ABT-263), a dual inhibitor of Bcl-2 and Bcl-XL , in patients with cancer.

    Journal of clinical pharmacy and therapeutics·2014
    Same author

    EVAR deployment in anatomically challenging necks outside the IFU.

    European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery·2013
    Same author

    EVAR using the Nellix Sac-anchoring endoprosthesis: treatment of favourable and adverse anatomy.

    European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery·2011
    Same author

    Chronic homocysteine exposure upregulates endothelial adhesion molecules and mediates leukocyte: endothelial cell interactions under flow conditions.

    European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery·2010
    Same author

    Ruptured abdominal aortic aneurysm: a surgical emergency with many clinical presentations.

    Postgraduate medical journal·2009

    Area of Science:

    • Vascular Surgery
    • Interventional Cardiology

    Background:

    • Profundaplasty is utilized for aortofemoral graft complications and as a primary treatment for severe limb ischemia.
    • Its efficacy as an isolated procedure for limb salvage remains debated.

    Purpose of the Study:

    • To evaluate the outcomes of profundaplasty in patients with threatened aortofemoral graft failure versus isolated limb ischemia.
    • To assess the predictive value of preoperative angiographic criteria for profundaplasty success.

    Main Methods:

    • Retrospective review of 27 patients undergoing profundaplasty (1978-1983).
    • Patients were divided into two groups: threatened graft failure (n=5) and isolated limb ischemia (n=22).
    • Preoperative angiograms were analyzed for five specific criteria predictive of favorable outcomes.

    Main Results:

    • Profundaplasty achieved 100% success in patients with threatened graft failure.
    • Only 14% of patients undergoing isolated profundaplasty for limb salvage experienced symptom relief or lesion healing.
    • 64% of patients in the isolated limb salvage group required major amputation.

    Conclusions:

    • Profundaplasty is a valuable outflow procedure for aortofemoral grafts but is not recommended as an isolated treatment for limb salvage.
    • Preoperative angiographic criteria are not reliable in identifying patients who will benefit from isolated profundaplasty.
    • The primary role of profundaplasty is to enhance outflow for aortic grafts.

    Related Experiment Videos