Emerging Bioprinting for Wound Healing.

Area of Science:

• Biomedical Engineering
• Materials Science
• Regenerative Medicine

Background:

• Bioprinting is a key technology for fabricating advanced biomedical devices.
• Smart wound dressings fabricated using bioprinting offer tailored structures and functions for enhanced skin regeneration.

Purpose of the Study:

• To provide a comprehensive review of bioprinting techniques for smart wound dressings.
• To emphasize the role of bioprinting in controlling biostructures and biofunctions for wound healing applications.

Main Methods:

• Overview of bioprinting techniques and devices.
• In-depth discussion of polymer-based inks, modification strategies, additives, properties, and applications.
• Categorization of modification strategies including chemical synthesis, physical blending, coaxial, multimaterial, absorption, immobilization, and cell hybridization.

Main Results:

• Bioprinting allows precise control over the design of wound dressings, matching wound site geometry and promoting regeneration.
• Various modification strategies enhance the functionality of bioprinted devices.
• Emerging frontiers include 4D bioprinting, AI-assisted bioprinting, and in situ bioprinting.

Conclusions:

• Bioprinting is crucial for developing advanced smart wound dressings.
• Interdisciplinary approaches and emerging technologies promise significant advancements in bioprinted wound healing.
• Addressing current challenges is essential for future prospects in this field.