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Behavioral self-regulation in pediatric bipolar disorder and healthy offspring of bipolar patients

Cristiana C A Rocca1, Sheila C Caetano2, Gabriel Okawa Belizario3

  • 1Programa de Transtorno Bipolar, Departamento de Psiquiatria, Universidade de São Paulo (USP), São Paulo, SP, Brazil. Núcleo de Apoio à Pesquisa em Neurociência Aplicada, USP, São Paulo, SP, Brazil. Laboratórios Integrados de Neuropsicologia, Instituto de Psiquiatria, Hospital das Clínicas, Faculdade de Medicina, USP, São Paulo, SP, Brazil.

Revista Brasileira De Psiquiatria (Sao Paulo, Brazil : 1999)
|August 11, 2023
PubMed

Insights

Children with pediatric bipolar disorder (PBD) exhibit significant behavioral self-regulation issues, including hostility and aggression, compared to healthy controls. These problems were not significantly different in healthy offspring of bipolar disorder patients (HOBD).

Area of Science:

  • Child and Adolescent Psychiatry
  • Behavioral Psychology
  • Neurodevelopmental Disorders

Background:

  • Behavioral self-regulation is crucial for healthy development.
  • Pediatric bipolar disorder (PBD) is associated with significant behavioral challenges.
  • Understanding self-regulation deficits in PBD is vital for effective interventions.

Purpose of the Study:

  • To investigate behavioral self-regulation problems in pediatric bipolar disorder (PBD).
  • To compare self-regulation difficulties in PBD, healthy offspring of bipolar disorder patients (HOBD), and healthy controls (HC).
  • To utilize the Children's Hostility Inventory (CHI) for assessment.

Main Methods:

  • The Children's Hostility Inventory (CHI) was administered to 41 children with PBD, 16 HOBD, and 22 HC.
  • The CHI assessed irritability, expression, hostility, and aggression.
  • Diagnostic interviews (K-SADS-PL) were conducted with participants and parents.

Main Results:

  • Statistically significant differences were found across most CHI subscales between groups.
  • The PBD group showed significantly higher levels of hostility and aggression compared to both HOBD and HC groups.
  • No significant differences in self-regulation problems were observed between the PBD and HOBD groups.

Conclusions:

  • Behavioral self-regulation difficulties, particularly hostility and irritability, are prominent in PBD.
  • These behaviors may represent a trait or state-dependent characteristic in juvenile bipolar disorder.
  • Psychosocial interventions targeting hostility and irritability are recommended for PBD.
Abstract

Keywords:
Pediatric bipolar disorderbipolar offspringhostilityirritabilityself-regulation

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