Towards the design of mechanical flexible electrodes for sensing: Self-standing polypyrrole-copper nanocomposites

Self-standing electrodes with intrinsic conductivity and high electrocatalytic activity emerge as an alternative to existing sensors given their promising flexibility and wearability. Herein we demonstrate the fabrication of flexible sensors based on a hybrid nanocomposite of self-supported polypyrrole electrodes modified with copper nanoparticles (PPy-Cu) for the electrochemical detection of dopamine. The surface morphology and composition of flexible nanocomposite electrodes was studied using scanning electron microscopy (SEM), in combination with elemental mapping through energy dispersive X-ray spectroscopy (EDS). Surface characterization by X-ray photoelectron spectroscopy (XPS) revealed that copper exists in both Cu(0) and Cu(II) forms. The incorporation of copper nanoparticles in the self-standing polypyrrole matrix introduced additional electroactive sites, further enhancing charge transfer, and improving the device's sensitivity. The sensing capability of self-standing PPy-Cu electrodes was evaluated using chronoamperometric measurements and optimized at various copper electrodeposition times. PPy-Cu 120s showed great performance for dopamine sensing with a low limit of detection of 1.19 μM and a linear range of 2.5 μM-250 μM. Additionally, the self-standing sensor is comprised entirely of Polypyrrole, a biocompatible polymer, and Copper nanoparticles, making it sustainable and environmentally friendly. These encouraging results pave the way for the development of next-generation flexible sensors for the detection of neurotransmitters and environmentally relevant analytes.