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Asthma in the era of COVID-19

Sara Assaf1, Henning Stenberg2, Milos Jesenak3

  • 1Section of Pulmonary and Critical Care Medicine, University of New Mexico, Albuquerque, NM, USA.

Respiratory Medicine
|August 11, 2023
PubMed

Insights

Patients with asthma face varying COVID-19 risks based on their specific condition and comorbidities. Current asthma treatments, including inhaled corticosteroids and biologics, do not appear to increase adverse COVID-19 outcomes.

Area of Science:

  • Pulmonology
  • Infectious Diseases
  • Public Health

Background:

  • COVID-19 (coronavirus disease 2019) significantly impacted global health and healthcare systems since 2019.
  • Asthma patients were initially considered at higher risk for SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) infection and severe outcomes.
  • Emerging evidence indicates that asthma phenotypes, endotypes, and comorbidities, rather than asthma itself, dictate risk stratification.

Approach:

  • This review synthesizes current evidence on COVID-19 in asthma patients.
  • It examines susceptibility, clinical manifestations, and disease course.
  • Recommendations for managing asthma patients during the pandemic are discussed.

Key Points:

  • Asthma's impact on COVID-19 risk is nuanced, influenced by individual patient factors.
  • Inhaled corticosteroids and biologic therapies for asthma have not shown increased risk for severe COVID-19.
  • Understanding specific asthma profiles is crucial for accurate risk assessment.

Conclusions:

  • The relationship between asthma and COVID-19 is complex and multifactorial.
  • Asthma management strategies should be individualized, considering both conditions.
  • Continued research is needed to refine care for this patient population.

Keywords:
AsthmaBiologicalsCOVID-19Long COVIDPhenotypes

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