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Diagnostic difficulties in pediatric annular dermatoses

Doris Weiss1, Philipp Weber1, Amélie Hampel1

  • 1Department of Dermatology, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria.

Wiener Medizinische Wochenschrift (1946)
|August 11, 2023
PubMed

Insights

Pediatric annular dermatoses present diagnostic challenges. This case highlights Wells' syndrome with histological features of annular erythema of infancy, prompting a review of differential diagnoses.

Area of Science:

  • Pediatric Dermatology
  • Dermatopathology
  • Clinical Diagnosis

Background:

  • Annular dermatoses in children exhibit diverse presentations, complicating diagnosis.
  • Differential diagnosis includes distinct entities like annular erythema of infancy (AEI) and eosinophilic annular erythema (EAE).
  • Wells' syndrome (WS) is an eosinophilic dermatosis characterized by dermal eosinophilic infiltration and flame figures.

Purpose of the Study:

  • To report a pediatric case with clinical Wells' syndrome and histological findings suggestive of AEI.
  • To discuss the differential diagnoses of annular dermatoses in children.
  • To review the similarities and distinctions between AEI and EAE.

Main Methods:

  • Case report of a young girl with annular dermatosis.
  • Clinical assessment and histopathological examination.
  • Literature review of pediatric annular dermatoses, AEI, EAE, and WS.

Main Results:

  • The patient presented with clinical features consistent with Wells' syndrome.
  • Histological examination revealed findings favoring annular erythema of infancy (AEI).
  • Morphological and histological overlap between AEI and EAE was noted.

Conclusions:

  • The case underscores the diagnostic challenges posed by pediatric annular dermatoses.
  • Distinguishing between AEI and EAE requires careful clinicopathological correlation.
  • A comprehensive review of differential diagnoses is crucial for accurate pediatric dermatosis management.

Keywords:
Annular erythema of infancyEosinophilic annular erythemaEosinophilic dermatosesWells’ syndrome

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