Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Overweight and mortality.

L Garfinkel

    Cancer
    |October 15, 1986
    PubMed
    Summary
    This summary is machine-generated.

    Obesity significantly increases mortality risk from all causes, heart disease, diabetes, and digestive diseases. Obese individuals also face higher cancer mortality, particularly men with prostate cancer and women with endometrial and gallbladder cancers.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    [Changes in the bronchial epithelium in relation to the tobacco habit and to carcinoma of the lung].

    Revista mexicana de tuberculosis y enfermedades del aparato respiratorio·2014
    Same author

    U.S. cancer incidence, mortality and survival: 1973-1996.

    Statistical bulletin (Metropolitan Life Insurance Company : 1984)·1999
    Same author

    Mortality hazard associated with prescription hypnotics.

    Biological psychiatry·1998
    Same author

    Trends in cigarette smoking in the United States.

    Preventive medicine·1997
    Same author

    Oscar Auerbach, M.D.: in memoriam.

    Cancer·1997
    Same author

    Twenty-year follow-up of the breast cancers diagnosed during the Breast Cancer Detection Demonstration Project.

    CA: a cancer journal for clinicians·1997
    Same journal

    Long-term outcomes of evolving treatment regimens in Ewing sarcoma survivors diagnosed 1970-1999: A report from the Childhood Cancer Survivor Study.

    Cancer·2026
    Same journal

    Large-scale osteosarcoma sequencing reveals age-associated genomic architectures.

    Cancer·2026
    Same journal

    EZH2 inhibitor tazemetostat voluntarily withdrawn from market.

    Cancer·2026
    Same journal

    Nivolumab and chemotherapy combination approved for previously untreated Hodgkin lymphoma.

    Cancer·2026
    Same journal

    Most older patients with advanced cancer prioritize QOL over extending survival: A secondary analysis of the GAP70+ trial found that among adults aged 70 and older with advanced, noncurable cancer, nearly three-quarters prioritized maintaining QOL.

    Cancer·2026
    Same journal

    Real-world safety, prognostic, and design considerations in ketogenic diet trials for pancreatic cancer.

    Cancer·2026
    See all related articles

    Area of Science:

    • Epidemiology
    • Public Health
    • Medical Research

    Background:

    • Obesity is a growing public health concern linked to various chronic diseases.
    • Understanding the specific mortality risks associated with different weight categories is crucial for preventative strategies.

    Purpose of the Study:

    • To investigate the relationship between relative weight categories and mortality ratios in a large cohort.
    • To identify specific causes of death and cancer sites with elevated mortality risks in overweight and obese individuals.

    Main Methods:

    • Analysis of mortality data from a prospective study of 750,000 men and women (1960-1972).
    • Comparison of mortality ratios across different relative weight categories against average weights.
    • Stratification of mortality by cause of death, including all causes, coronary heart disease, diabetes, digestive diseases, and specific cancers.

    Related Experiment Videos

    Main Results:

    • Overweight individuals (40% or more above average weight) exhibited a 1.87-1.89 increased mortality ratio for all causes.
    • Elevated mortality ratios were observed for coronary heart disease, diabetes, and digestive diseases in overweight populations.
    • Obese men showed a 1.33 mortality ratio for cancer, while obese women had a 1.55 ratio. Specific cancer sites with high mortality included colon-rectum and prostate in men, and endometrium, cervix, gallbladder, ovary, and breast in women.

    Conclusions:

    • Significant increases in all-cause mortality and mortality from specific chronic diseases are associated with being overweight.
    • Obesity is linked to substantially higher mortality rates for several types of cancer, with notable variations between sexes and cancer sites.