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Related Experiment Video

Updated: Jul 19, 2025

Granulocyte-dependent Autoantibody-induced Skin Blistering

Granulocyte-dependent Autoantibody-induced Skin Blistering

Published on: October 12, 2012

Interventions for bullous pemphigoid.

Sanjay Singh¹, Gudula Kirtschig², Vinayak N Anchan¹

¹Department of Dermatology and Venereology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India.

The Cochrane Database of Systematic Reviews

|August 12, 2023

Summary

This summary is machine-generated.

Topical clobetasol propionate cream and oral doxycycline show promise for treating bullous pemphigoid (BP), a common autoimmune blistering disease. These treatments may offer improved outcomes and reduced mortality compared to traditional oral steroids.

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Last Updated: Jul 19, 2025

Granulocyte-dependent Autoantibody-induced Skin Blistering

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Published on: October 12, 2012

A Standardized Procedure of Dressing Management for Toxic Epidermal Necrolysis

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Published on: March 14, 2025

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis

Published on: July 11, 2013

Area of Science:

Dermatology
Autoimmune Diseases
Pharmacology

Background:

Bullous pemphigoid (BP) is the most prevalent autoimmune blistering disease.
Oral steroids are the conventional treatment, but newer therapies are being investigated.
This review is an update of a previous 2002 publication.

Conclusions:

Topical clobetasol propionate cream is a viable alternative to oral prednisone for BP, with potential for reduced mortality.
Doxycycline offers a safer profile than prednisolone, despite lower efficacy in skin healing.
Further research is needed for other emerging treatments for bullous pemphigoid.