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Updated: Jul 19, 2025
High Frequency Ultrasound for the Analysis of Fetal and Placental Development In Vivo
Published on: November 8, 2018
Perceiving placental ultrasound image texture evolution during pregnancy with normal and adverse outcome through
Urvashi Arora1, Debarka Sengupta1, Manisha Kumar2
1Indraprastha Institute of Information Technology Delhi, New Delhi, India.
Introduction:
The objective was to perform placental ultrasound image texture (UPIA) in first (T1), second(T2) and third(T3) trimesters of pregnancy using machine learning( ML).
Methods:
In this prospective observational study the 2D placental ultrasound (US) images from 11-14 weeks, 20-24 weeks, and 28-32 weeks were taken. The image data was divided into training, validating, and testing subsets in the ratio of 80%, 10%, and 10%. Three different ML techniques, deep learning, transfer learning, and vision transformer were used for UPIA.
Results:
Out of 1008 cases included in the study, 59.5% (600/1008) had a normal outcome. The image texture classification was compared between T1&T2, T2 &T3 and T1&T3 pairs. Using Inception v3 model, to classify T1& T2 images, gave the accuracy, Cohen Kappa score of 83.3%, 0.662 respectively. The image classification between T1&T3 achieved best results using EfficientNetB0 model, having the accuracy, Cohen Kappa score, sensitivity and specificity of 87.5%, 0.749, 83.4%, and 88.9% respectively. Comparison of placental image texture among cases with materno-fetal adverse outcome and controls was done using Efficient Net B0. The F1 score, was found to be 0.824 , 0.820, and 0.892 in T1, T2 and T3 respectively. The sensitivity and specificity of the model was 77.4% at 80.2% at T1 but increased to 81.0% and 93.9% at T2 &T3 respectively.
Discussion:
The study presents a novel technique to classify placental ultrasound image texture using ML models and could differentiate first and third-trimester normal placenta and normal and adverse pregnancy outcome images with good accuracy.
