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Heterochromatinization of human X-chromosomes: classification of replication profile
Clinical Genetics
|August 1, 1986
Abstract:
The replication profiles of human X-chromosomes are studied by RBA-technique. It is suggested that the late replicating X-chromosome can be arbitrarily classified into 8 types. Furthermore, data suggest that the individual cells are under self-control pertaining to the inactivated X-chromosome. This may reflect that the altered chromatin may not be uniform in the process of inactivation.