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Viral Nanoparticles for In vivo Tumor Imaging
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Viral nanoparticles: Current advances in design and development
Siva Santhiya Arul1, Brinda Balakrishnan1, Savithri S Handanahal2
1Department of Biotechnology, Anna University, Chennai, 600025, India.
Biochimie
|August 12, 2023
Summary
Viral nanoparticles (VNPs) offer adaptable delivery for vaccines and therapeutics. Advances in VNP platforms address challenges in large-scale production for diverse biomedical applications.
Area of Science:
- Biomedical Engineering
- Nanotechnology
- Virology
Background:
- Viral nanoparticles (VNPs) are self-assembling nanocarriers derived from viruses.
- They possess inherent biocompatibility, biodegradability, and immunogenic properties.
- VNPs can be engineered for targeted delivery of therapeutic payloads.
Purpose of the Study:
- To review recent advances in viral nanoparticle applications.
- To highlight the potential of VNPs in various biomedical fields.
- To discuss challenges and emerging solutions in VNP production.
Main Methods:
- Review of current literature on viral nanoparticle research.
- Analysis of genetic and chemical engineering strategies for VNP modification.
- Exploration of diverse viral platforms for VNP development.
Main Results:
- VNPs are utilized in cancer therapy, vaccine development, diagnostics, and molecular imaging.
- Emerging applications include tissue engineering, biosensing, and antimicrobial prophylaxis.
- New platforms using plants and microorganisms are being developed to overcome production challenges.
Conclusions:
- Viral nanoparticles represent a versatile platform for advanced biomedical applications.
- Continued research into VNP engineering and production is crucial for clinical translation.
- Addressing scalability and cost-effectiveness will enable wider adoption of VNPs.

